Azabicycloalkenes as Synthetic Intermediates — Synthesis of Azabicyclo[X.3.0]alkane Scaffolds.
نویسندگان
چکیده
منابع مشابه
Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates.
The synthesis of (+/-)-1'-epi-stegobinone has been accomplished in ten steps and 17% overall yield from a recently reported silacyclopropane-derived diol. All stereocenters of the final product were established relative to the stereochemistry of the initial silacyclopropane. This synthesis represents the first time silacyclopropane reactivity has been employed in a target-directed synthesis.
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BACKGROUND Tandem olefin metathesis sequences are known to be versatile for the generation of natural product scaffolds and have also been used for ring opening of strained carbo- and heterocycles. In this paper we demonstrate the potential of these reactions for the desymmetrization of 7-azabicycloalkenes. RESULTS We have established efficient protocols for the desymmetrization of different ...
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چکیده ندارد.
Synthetic scaffolds for pathway enhancement.
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ژورنال
عنوان ژورنال: ChemInform
سال: 2007
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200714158